Past Events

June 16th 20215th Boston Area Drosophila Meeting | The Whitehead Institute

Virtual Meeting due to the COVID-19 pandemic.

To view a PDF version of the schedule, click here.

12:30– 1:55 pm Session 1: Concurrent Sessions

NeurobiologyModerator: Jens Rister, University of Massachusetts Boston
12:30 – 12:45 pmWelcoming Remarks
Ruth Lehmann, Whitehead Institute, Massachusetts Institute of Technology
12:45 – 1:00 pmKimberly Madhwani, O’Connor-Giles lab, Brown University
Neurodevelopmental role of a tRNA regulator underlying intellectual disability
1:00 – 1:15 pmPaul Marcogliese, Bellen lab, Baylor College of Medicine
Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling
1:15 – 1:30 pmChad Sauvola, Littleton lab, Massachusetts Institute of Technology
Drosophila Tomosyn regulates tonic/phasic release differences and is required for presynaptic homeostatic potentiation
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Mohamed Adel, Griffith lab, Brandeis University
Establishing an ex vivo model for aversive associative learning in fruit flies
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Sabrina Clemens, Olsen lab, Harvard Medical School
A Drosophila model for validating gene-environment interactions in Parkinson’s disease
1:30 – 1:45 pmAne Martin Anduaga, Kadener lab, Brandeis University
Thermosensitive alternative splicing of timeless senses and mediates temperature adaptation in Drosophila
1:45 – 1:55 pmTorrey Mandigo, Walker lab, Mass General Hospital
Drosophila modeling of a human sleep/chronotype GWAS locus highlights a conserved role for the N-glycosylation pathway in the sleep-epilepsy axis
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Matthias Schlichting, Rosbash lab, Brandeis University
Dopaminergic input to the Drosophila clock neuron network promotes sleep
GametogenesisModerator: Vicki Losick, Boston College
12:30 – 12:45 pmWelcoming Remarks
Yukiko Yamashita, Whitehead Institute, Massachusetts Institute of Technology, Howard Hughes Medical Institute
12:45 – 1:00 pmJianjun Sun, University of Connecticut
A novel platform utilizing Drosophila ovulation for non-hormonal contraceptive screenings
1:00 – 1:15 pmMadhumala Sadanandappa, Bosco lab, Darmouth College
Parasite-activated neuronal circuits trigger Drosophila germline modification
1:15 – 1:30 pmAri Dehn, Losick lab, Boston College
Modeling age-induced polyploidy in Drosophila
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Hammed Badmos, Cagan lab, University of Glasgow
The role of SAGA components in cell migration and epithelial integrity
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Diane Lebo, McCall lab, Boston University
Molecular regulation of clearance by nonprofessional phagocytes in the Drosophila ovary
1:30 – 1:45 pmStacey Hanlon, University of Connecticut
Female meiotic drive of B chromosomes in D. melanogaster
1:45 – 1:50 pmJiaxin Gong, Xiang lab, UMASS Medical School
Shear stress activation of TrpA1 underlies mechanical nociception in Drosophila Melanogaster

2:00 – 3:00 pm Keynote Speaker Address

Flies to study disease associated variants and pathogenic mechanisms

Hugo J. Bellen, D.V.M., Ph.D., is an Investigator of the Howard Hughes Medical Institute, the March of Dimes Professor in Developmental Biology and Charles Darwin Professor in Genetics at Baylor College of Medicine in the Departments of Molecular and Human Genetics, and Neuroscience, and the Neurological Research Institute at Texas Children’s Hospital.

3:00 – 3:15 pm Break

3:15 – 4:00 pm Workshops

Workshop 1
Genetic/Genomic Technologies
Host: Norbert Perrimon, Harvard Medical School, Broad Institute
Workshop 2
Modeling Human Disease
Host: Hugo Bellen, Baylor College of Medicine, Howard Hughes Medical Institute
3:15 – 3:26 pm Hongjie Li, Baylor College of Medicine
Update on the Fly Cell Atlas
China Byrns, Bonini lab, University of Pennsylvania
Glial AP1 promotes early traumatic brain injury recovery but chronically drives tauopathy
3:26 – 3:37 pm Julie Agapite, Harvard University
What’s new at FlyBase
Sayantanee Paul, Veraksa lab, University of Massachusetts Boston
ERK-mediated phosphorylation of Capicua, a key regulator of MAPK signaling in development and disease
3:37 – 3:48 pm Justin Bosch, Perrimon lab, Harvard Medical School
Proximity labeling: Application to the fly blood secretome
Guang Lin, Bellen lab, Baylor College of Medicine
Altered ceramide metabolism and endolysosomal pathway in the pathogenesis of INAD/PARK14
3:48 – 4:00 pm Jun Xu, Perrimon lab, Harvard Medical School
New Nanotag-Nanobody tools for in vivo studies
Liping Wang, Bellen lab, Baylor College of Medicine
Glucosylceramide is generated by active neurons and transported to glia for lysosomal degradation by Glucosylceramidase (GBA)

4:00 – 4:45 pm Round Table Discussions

Career Trajectories in Drosophila ResearchToward Inclusive Diversity: Steps we can take in our labs, classrooms, and institutions
Hosts:
Alexis Hill
College of the Holy Cross
How to find a position in academia

Kristin White
Mass. General Hospital, Harvard Medical School
The pros and cons of a job in academia

Susan Gerbi
Brown University
Defining your strengths and weaknesses,
job shadowing and networking
Host:
Michele Markstein
Princeton University
University of Massachusetts Amherst

4:45 – 5:00 pm Break

5:00 – 6:00 pm Session 2: Concurrent Sessions

MorphogenesisModerator: Erica Larschan, Brown University
5:00 – 5:15 pmMukulika Ray, Larschan lab, Brown University
Maternal pioneer factor CLAMP regulates sex-specific transcript diversity in early Drosophila embryos
5:15 – 5:25 pmJacob Malin, Hatini lab, Tufts University
Sidekick alternately interacts with contractile and protrusive effectors to control epithelial morphogenesis
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Mary Ann Collins, Martin lab, Massachusetts Institute of Technology
Actin Interacting Protein 1 promotes tissue fusion via intercellular force transmission during Drosophila gastrulation
5:25 – 5:40 pmKevin Cabrera, Wunderlich lab, University of California, Irvine
Transcriptional mechanisms controlling immune priming in Drosophila melanogaster
5:40 – 6:00 pmClosing Remarks
Ruth Lehmann, Whitehead Institute, Massachusetts Institute of Technology
Transposable ElementsModerator: Nelson Lau, Boston University School of Medicine
5:00 – 5:15 pmJonathan Nelson, Yamashita lab, Whitehead Institute
The essential role of retrotransposons to maintain ribosomal DNA in the Drosophila male germline
5:15 – 5:25 pmJoyce Rigal, Marr lab, Brandeis University
Increasing somatic transposon activity shortens D. melanogaster’s lifespan
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Niraj Kumar Nirala, UMASS Medical School
The Hinfp-Histone1 axis represses transposable elements to safeguard somatic genomes
5:25 – 5:40 pmNick Rice, Theurkauf lab, UMASS Medical School
Heat stress disrupts piRNA biogenesis machinery
5:40 – 6:00 pmClosing Remarks
Yukiko Yamashita, Whitehead Institute, Massachusetts Institute of Technology, Howard Hughes Medical Institute

June 11th 2020 – 4th Boston Area Drosophila Meeting | Boston University

Virtual Meeting due to the COVID-19 pandemic.

LOCAL ORGANIZERS
Kim McCall | Prof. & Chair of Biology, Boston University
Nelson Lau | Assoc. Prof., Boston University School of Medicine

KEYNOTE SPEAKER

Dr. Ruth Lehmann,  currently the Laura and Isaac Perlmutter Professor of Cell Biology and Chair of the Department of Cell Biology at New York University (NYU),  and incoming director of the Whitehead Institute at MIT.


AGENDA

12:30 PM – 12:35 PM Welcoming Remarks
Kim McCall, Horacio Frydman, the BADM Committee
12:35 PM – 1:30 PM Vertical transmission of Wolbachia in Drosophila gut cells and its effects in stem cell division
Natalie Vaisman, Frydman lab, Boston University
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Zombiflied: Interrogating the mechanistic basis of behavior manipulation using the “zombie” entomopathogen Entomophthora muscae
Carolyn Elya, de Biovort Lab, Harvard University
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Two peptides encoded from a single transcript regulate mitochondrial function in Drosophila
Justin Bosch, Perrimon Lab, Harvard Medical School
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Investigation of variant PRC1 complexes in Drosophila
Janel Cabrera, Emmanuel College
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Wound-induced polyploidization: an adaptive healing strategy
Vicki Losick, Boston College
1:30 PM – 1:35 PM BREAK
1:35 PM – 2:35 PM Role of the Circular RNA Edis in Innate Immunity and Neurodevelopment
Rui Zhou, Johns Hopkins All Children’s Hospital
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Defining a critical glial role for Parkinson’s disease risk genes in controlling alpha-synuclein toxicity
Abby Olsen, Feany Lab, Harvard Medical School
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Operant Conditioning to a Food Reward Requires Rest
Timothy Wiggin, Griffith Lab, Brandeis University
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Flexible cross-inhibition controls Drosophila larva thermotaxis
Luis Hernandez, Samuel Lab, Harvard University
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Internal state configures olfactory behavior and early sensory processing in Drosophila larvae
Katrin Vogt, Samuel Lab, Harvard University
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Open bar assay: A reward self-administration paradigm for studying drug and substance use disorders
John Hernandez, Kaun Lab, Brown University
1:35 PM – 2:35 PM Regulation of epidermal cell differentiation by the Hippo pathway and Bonus
Heya Zhao, Veraksa Lab, University of Massachusetts – Boston
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Modeling Genomic Complexity of Colorectal Cancer using Multi-genic Drosophila Models
Sindhura Gopinath, Cagan Lab, Mt. Sinai
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An auto-inhibitory clamp of actin assembly promotes synaptic endocytosis
Steven Del Signore, Rodal Lab, Brandeis University
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Nuclear receptor Ftz-f1 promotes follicle maturation and ovulation partly via bHLH/PAS transcription factor Sim
Jianjun Sun, University of Connecticut
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The Ecdysone response pathway differentially regulates the Hippo pathway in two subtypes of post-mitotic photoreceptors
Joseph Bunker, Rister Lab, University of Massachusetts – Boston
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Dietary Stress Affects Structure and Function of the Eye
Khanh Lam-Kamath, Rister Lab, University of Massachusetts – Boston
1:35 PM – 2:35 PM Investigating the relationship between genome organization of paired chromosomes and genome function at the single cell level in Drosophila
Jumana AlHaj Abed, Wu Lab, Harvard Medical School
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Regulatory mutations play the major role in the evolution of gene activity
David Loehlin, Williams College
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De novo evolved genes are essential for Drosophila male fertility and act at multiple stages of spermatogenesis
Geoff Findlay, College of the Holy Cross
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Transcriptional changes in Drosophila genome during vitamin A deprivation
Deepshe Dewett, Rister Lab, University of Massachusetts – Boston
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Aging leads to changes in transposable element landscapes in Drosophila
Nachen Yang, Lau Lab, Boston University
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Har-P, a short P-element variant, weaponizes P-transposase to severely impair Drosophila development
Nelson Lau, Boston University
2:35 PM – 2:55 PM BREAK
2:55 PM – 3:25 PM Neurobiology & Behavior
Paul Garrity, Professor at Brandeis University, Discussion Leader
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CRISPR & Other Tools
Stephanie Mohr, Director of DRSC/TRiP-FGR at Harvard Medical School, Discussion Leader
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Human Disease Modeling & Metabolism
Marla Tipping, Assistant Professor at Providence College, Discussion Leader
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Gene Regulation & Epigenetics
Jens Rister, Assistant Professor at University of Massachusetts – Boston, Discussion Leader
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Stem Cells & Development
Kristin White, Associate Professor at MGH/Harvard Medical School, Discussion Leader
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Diversity & Science in a Pandemic
Michelle Markstein, Assistant Professor at University of Massachusetts – Amherst, Discussion Leader
3:30 PM – 4:15 PM KEYNOTE – Germ cells are forever
Dr. Ruth Lehmann, Laura and Isaac Perlmutter Professor of Cell Biology, New York University; Incoming Director of the Whitehead Institute, Massachusetts Institute of Technology
4:15 PM – 5:30 PM A non-canonical odor receptor mediates responses to the widely attractive odor ammonia
Karen Menuz, University of Connecticut
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Sleep loss can cause death through accumulation of reactive oxygen species in the gut
Yosef Kaplan Dor, Rogulja Lab, Harvard Medical School
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Persistent Calcium Spikes Are an Axon Injury Signal Controlling Subtype-specific Regeneration
Fei Wang, Xiang Lab, University of Massachusetts Medical School
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“Disease-relevant” to disease model: how FlyBase can help you investigate human disease in Drosophila
Victoria Jenkins, FlyBase
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A flexible new platform for insect cell biology: pooled genome-wide CRISPR screens
Raghuvir Viswanatha, Harvard Medical School
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Online Bioinformatics Resources from the DRSC/TRiP
Claire Hu, Director of Bioinformatics, DRSC/TRiP-FGR, Harvard Medical School
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Large-scale transgenic Drosophila resource collections for loss- and gain-of-function studies
Jonathan Zirin, Director of in vivo Technologies, DRSC/TRiP-FGR,  Harvard Medical School
5:40 PM Closing Remarks
Nelson Lau, the BADM Committee

June 11th 2019 – 3rd Boston Area Drosophila Meeting | Brown University

LOCAL ORGANIZERS
Karla Kaun | Asst. Prof. of Neuroscience, Brown
Erica Larschan | Asst. Prof. of Biology, Brown
Nate Snell | Grad. Student, Barnea Lab, Brown
Jackie Howell | Grad. Student, Tatar & Kaun Labs, Brown
Mukulika Ray | Grad. Student, Larschan Lab, Brown

KEYNOTE SPEAKER
Avital Rodal

Avital Rodal
Associate Professor of Biology
Brandeis University

AGENDA
Downloadable Agenda (with abstracts)

9:30 AM – 10:30 AM Microtubules stabilize intercellular contractile force transmission during ventral furrow formation
Clint Ko, Martin Lab, Massachusetts Institute of Technology
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microRNA dependent regulatory switch that controls immune responses by regulating stem cell fate in the gut
Pushpa Verma, Van Vacter Lab, Harvard University
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Dissecting the sharp response of a canonical developmental enhancer reveals multiple sources of cooperativity
Jeehae Park, DePace Lab, Harvard Medical School
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[Lightning] KO or OK?: A computational method to uncover regulatory mechanisms of transcription factors during development
Ashley Conard, Larschan Lab, Brown University
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[Lightning] A myotubularin-related phosphatase that regulates autophagic flux
Elizabeth Allen, Baehrecke Lab, University of Massachusetts Medical School
10:30 AM – 10:45 AM BREAK
10:50 AM – 12:00 PM Drosophila DEG/ENaCs Expressed in Neurons and Muscle Impact Synaptic Transmission and Behavior
Alexis Hill, Assistant Professor, College of the Holy Cross
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A conserved role for the N-glycosylation pathway in sleep and seizures
Brittany Leger, Walker Lab, Massachusetts General Hospital
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Early integration of multimodal chemosensory stimuli in the Drosophila larva
Jess Kanwal, Samuel Lab, Harvard University
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[Lightning] Behavioral features of alcohol reinforcement in Drosophila
Jamie Catalano, Kaun Lab, Brown University
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[Lightning] Identifying hygrotaxis circuit elements in Drosophila
Tatevik Sarkissian, Garrity Lab, Brandeis University
12:00 PM – 1:25 PM LUNCH  Discussion Groups
Apoptosis and Neurodegeneration
Cell Signaling and Development
Neurobiology and Behavior
Transcription and Epigenetics
1:30 PM – 2:30 PM Vitamin A deprivation as a novel approach to identify neuroprotective molecules
Jens Rister, Principal Investigator, University of Massachusetts – Boston
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Killing time: Decoupling developmental apoptosis and neuroblast proliferation in Drosophila
Katherine Harding, White Lab, Massachusetts General Hospital
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Generation of neuronal diversity in the Drosophila optic lobes through development and evolution
Nikos Konstantinides, Desplan Lab, New York University
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[Lightning] Structure-function analysis of β-arrestin Kurtz reveals a critical role of receptor interactions in downregulation of GPCR signaling in vivo
Fei Chai, Veraksa Lab, University of Massachusetts – Boston
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[Lightning] Pigment dispersing factor (PDF) signaling: A novel pathway for memory regulation by the circadian clock
Johanna Flyer-Adams, Griffith Lab, Brandeis University
2:30 PM – 2:45 PM BREAK
2:50 PM – 3:50 PM Glial α-synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo
Abby Olson, Feany Lab, Brigham & Women’s Hospital
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Regulation of endosomal Microautophagy in Drosophila
Ana Mesquita, Jenny Lab, Albert Einstein College of Medicine
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Selective Serotonin Reuptake Inhibitors as Potential Therapeutics for MEGF10 Myopathy
Isabelle Draper, Principal Investigator, Tufts Medical Center
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A new GFP-tagged cell line resource from the DRSC
Stephanie Mohr, Perrimon Lab / DRSC, Harvard Medical School
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[Lightning] – FlyBase Updates
Victoria Jenkins, FlyBase, Harvard University
3:50 PM – 4:00 PM BREAK
4:05 PM – 5:15 PM KEYNOTE – Routing and remodeling membranes at the synapse
Avital Rodal, Brandeis University
5:15 PM Dinner out in Providence

June 6th 2018 – 2nd Boston Area Drosophila Meeting | Harvard Medical School

LOCAL ORGANIZERS

Stephanie Mohr | Director, Drosophila RNAi Screening Center (DRSC), Harvard Medical School

KEYNOTE SPEAKER
Michael-Rosbash

Michael Rosbash
Peter Gruber Endowed Chair in Neuroscience, Professor of Biology | Brandeis University
Howard Hughes Medical Institute Investigator
Nobel Laureate – Physiology or Medicine (2017)

AGENDA

9:30 AM – 9:45 AM NKT is required in the mushroom body for night sleep regulation.
Lauren Crowe, R. Jackson Lab, Tufts University
9:45 AM – 10:00 AM Does the fly larva get hungry? How internal state affects olfactory preference.
Katrin Vogt, A. Samuel lab, Harvard University
10:00 AM – 10:15 AM Kinetochore proteins have a post-mitotic function in Drosophila neurodevelopment.
Guoli Zhao, T. Schwarz Lab, Boston Children’s Hospital & Harvard Medical School
10:15 AM – 10:30 AM Isoform-selective genome editing revealed expression and nociceptive function of Drosophila TrpA1 channel.
Yang Xiang, University of Massachusetts Medical School
10:30 AM – 10:45 AM Mapping neural circuits for alcohol reward in Drosophila.
Kristin Scaplen, K. Kaun Lab, Brown University
10:45 AM – 11:00 AM Plasma membrane localization of apoptotic caspases for non-apoptotic functions.
Alla Amcheslavsky, A. Bergmann Lab, University of Massachusetts Medical School
11:00 AM – 11:15 AM Mispositioned nuclei: Distinct mechanisms drive similar phenotypes.
Mary Ann Collins, Folker Lab, Boston College
11:15 AM – 11:20 AM [Lightning Talk] Restriction of apoptosis in Drosophila neuroblasts.
Katherine Harding, K. White Lab, Massachusetts General Hospital & Harvard Medical School
11:20 AM – 11:25 AM [Lightning Talk] The role of Hippo signaling in epithelial cell fate determination.
Heya Zhao, A. Veraksa Lab, University of Massachusetts, Boston
11:25 AM – 11:30 AM [Lightning Talk] Gene expression analysis in the developing ovary.
Shreeharsha Tarikere, C. Extavour Lab, Harvard University
11:30 AM – 1:00 PM LUNCH – Discussion Groups (NRB Cafeteria)
• Chromatin/DNA repair – Mitzi Kuroda
• Tools/Techniques/Disease models – Michele Markstein
• Neurobiology – Troy Littleton
• Cell death/apoptosis – Kristin White
1:00 PM – 1:15 PM Protein-protein interactions that modulate Polycomb function.
Hyuckjoon Kang, M. Kuroda Lab, Harvard Medical School
1:15 PM – 1:30 PM Mechanotransduction via the LINC complex regulates DNA replication and chromosome organization in myonuclei.
Shuoshuo Wang, T. Lionnet lab, New York University
1:30 PM – 1:45 PM BAD romance: enrichment of a fly dosage compensation GAGA motif in the human X chromosome.
Edridge D’Souza, M. Markstein lab, University of Massachusetts, Amherst
1:45 PM – 2:00 PM FlyBase 2018: new look, new features.
Gil dos Santos, FlyBase, Harvard University
2:00 PM – 2:15 PM Regulation of endosomal microautophagy by cellular stress in Drosophila.
Ana Mesquita, A. Jenny Lab, Albert Einstein College of Medicine
2:15 PM – 2:30 PM Disco modulates apoptosis and hyperplasia downstream of the Notch-JNK signaling axis.
Diana Ho, S. Artavanis-Tsakonas Lab, Harvard Medical School
2:30 PM – 2:45 PM Proteomics of protein trafficking by in vivo tissue-specific labeling.
Ilia Droujinine, N. Perrimon Lab, Harvard Medical School
2:45 PM – 2:50 PM [Lightning Talk] Trans inter-homolog pairing in haplotype-resolved genomes.
Jelena Erceg, T. Wu Lab, Harvard Medical School
2:50 PM – 2:55 PM [Lightning Talk] Probabilistic Modeling of Drosophila Sleep Reveals Mechanisms Regulating Sleep Duration and Structure.
Timothy Wiggin, L. Griffith Lab, Brandeis University
2:55 PM – 3:00 PM [Lightning Talk] TRiP CRISPR fly stock update.
J. Zirin, DRSC/TRiP-FGR, Harvard Medical School
3:00 PM – 3:30 PM BREAK
3:30 PM – 5:00 PM KEYNOTE ADDRESS: Michael Rosbash, Brandeis University
Introduction by Stephanie Mohr, Harvard Medical School

September 23rd 2016 – Boston Area Drosophila Meeting | University of Massachusetts Boston

LOCAL ORGANIZERS

Alexey Veraksa | Professor of Biology, University of Massachusetts, Boston
James Walker | Assistant Professor, Mass. General Hospital, Harvard Medical School

Screening of “The Fly Room” – Introduced by director, Alexis Gambisfly-room

AGENDA

Talks: Campus Center Ballroom (3rd Floor, Ballroom C)
Movie: University Hall, Room 2300

1:00 PM – 1:15 PM Resistance is Futile: Using the Fly to Overcome Stem Cell Drug Resistance
Michele Markstein, UMass Amherst
1:15 PM – 1:30 PM A new role of E2F in endocycling fatbody cells
Ana Guarner Peralta, N. Dyson Lab, Harvard Medical School
1:30 PM – 1:45 PM Ionotropic Receptors mediate detection of humidity
Zach Knecht, Paul Garrity Lab, Brandeis University
1:45 PM – 2:00 PM fs(1)h dependent neuroblast apoptosis
Antoine Borensztejn, K. White Lab, Harvard Medical School
2:00 PM – 2:15 PM Interaction of neurodegenerative APP and HTT proteins during axon growth via the proto-oncogene ABL
Lee Fradkin, UMass Medical School
2:15 PM – 2:30 PM Interaction between transcriptional co-activators and PRC1 on developmental genes
Hyuckjoon Kang, M. Kuroda Lab, Harvard Medical School
2:30 PM – 2:45 PM Serotonergic activity controls sleep architecture in Drosophila
Chang Liu, L. Griffith Lab, Brandeis University
2:45 PM – 3:15 PM Refreshment Break
3:15 PM – 3:30 PM Mechanisms of myonuclear movement
Torrey Mandigo, E. Folker Lab, Boston College
3:30 PM – 3:45 PM Functional genomics and bioinformatics resources at the HMS DRSC & TRiP 
Stephanie Mohr, Harvard Medical School
3:45 PM – 4:00 PM Optogenetic pacing in Drosophila melanogaster
Airong Li, Harvard Medical School
4:15 PM – 4:30 PM A new toolbox for the fly Sciara – a new/old model system
Susan Gerbi, Brown University
4:30 PM – 4:45 PM An optimized approach for CRISPR/Cas9-based transcriptional activation in vivo
Ben Ewen-Campen, N. Perrimon Lab, Harvard Medical School
4:45 PM – 5:00 PM Walk to University Hall, Room 2300
5:00 PM – 7:00 PM Introduction by Alexis Gambis and screening of “The Fly Room”